Abstract: Decontamination using foam means mixing air and foaming agent containing decontamination agent to form foam, which can be applied to the contaminated surface, so that the radionuclides are eliminated. By spraying or bubbling, the experiment studied the influence of stability agent and foaming agent concentration and air flow rate, etc. on the property of decontamination foam. The preliminary results show, the stability agent concentration is the main factor influencing hold-up time of foam, so the added mass concentration is suggested to be about 2 g/L, less than 3 g/L. Foaming agent concentration and air flow are the secondary influence factors, so the foaming agent mass concentration and air flow rate are suggested to be 8 g/L and 7.0 m³/h respectively. Optimization design is recommended, in order to obtain the best results.