Abstract: In order to simulate the hydrolytic polymerization behavior of Pu⁴⁺, the dynamic light scattering method was used to study the hydrolytic polymerization boundary conditions of Fe³⁺ in hydrochloric acid solution, and the thermodynamic function of hydrolytic polymerization was calculated using thermodynamic software HSC Chemistry 6.0. The results show that there is a certain correlation between c₀(H⁺), c(Fe³⁺) and temperature in the hydrolysis polymerization of Fe³⁺. Increasing Fe³⁺ concentration and temperature will promote Fe³⁺ hydrolysis polymerization. The particle size of the polymer colloid is more widely distributed with increasing Fe³⁺ concentration and temperature, and the median particle diameter is between 100 nm and 1000 nm.