Abstract: β-emitter radionuclides ⁹⁹Tc and ⁹⁰Sr are key research topics in environmental radio-chemistry. The radiochemical sensors can be used to measure these β-emitter radionuclides directly on site, meeting the monitoring requirements of ⁹⁹Tc and ⁹⁰Sr in environmental waters and liquid effluents of nuclear power plants, reprocessing plants, radioactive waste disposal facilities and radioisotope production facilities. The basic principles, dual functional resin, the structure of microcolumn, current status and the comparison with conventional analysis method were systematically discussed in this paper. And the main factors restricting the development of radiochemical sensors were pointed out, and some suggestions on the development of radiochemical sensor technology of β-emitter nuclides in our country were proposed.