Abstract: Xenon isotopes are produced by bombardment of 12C ions on natural indium target and can be satisfactorily separated from other products of the reaction by combination of the He-jet fast recoil transport system with a chemical separation method. 123Xe is identified and the relative chemical yield under cooling of liquid nitrogen is 80.7% with . decontamination factors 1 × 103 for cesium, gallium and germanium isotopes and over 1×102 for arsenic isotope. . ;