Abstract:
INDIRECT IODIZATION LABELLING OF CAMODULINZhang Zhongshu Xu Ruiji Wang Guohong Zhao Jiwen Shi Yiqun(Department of Nuclear Medicine,Nanjing General Hospital of PLA,Nanjing 210002)ABSTRACTThe iodinated calmodulin with 125I by the indirect iodination method is prepared.The specific radioactivity of 125ICaM is 1.56 MBq/μg,the total labelling rate of 125I is 23.1%. Clinical tests indicate that the specificity,stability and other technical specifications of the iodinated CaM can satisfy the needs of RIA for reducing the harm of direct iodination to the antigen.Key words Calmodulin 125I Indirect labelling