Abstract: PKODUCTION OF ~(67)Ga CITRATE INJECTION LIQUID WITH BUTYLACETATE EXTRACTION METHODFANG YIBING；LI BO；LIU PENG；PAN QIYUAN；LIU PEIHUA；WANG HAN；FENG JINGLING（Institute of High Energy Physics，Chinese Academy of Sciences，P.O.Box 918（11-04），Beijing 100039）ABSTRACT The distribution ratios D for Ga（Ⅲ）at trace concentration　in the HCl-butylacetate extrac-tion svstem are measured．It is showed that tHe D in 6 mol／l HCl 5×10~2 which is maximum in 3-8mol／l HCl．The extraction rates E in 5．5-8mol／l HCl at phase ratio of 1 are≥98％and≥96％respectively when the concentration of ZnCl_2 in the solution are 0 and≤2mol／l．A buty-lacetate extraction method for the production of ~(67)7Ga citrate injection liquid from Zn target irradi-ated by proton beam is developed．The optimal acidity of extraction is 6 mol／l HCl．The concen-tration of ZnCl_2 is adjusted to≤2．0mol／l　and the impurity of Fe（Ⅲ）in solution is reduced toFe（Ⅱ）with 10％TiCl_3 before extraction.The ~(67)Ga in organic phase is then stripped with water.The radionuclidic purity of the product is 100％while the radiochemical purity ＞ 90％.Theamounts of Zn，Ti，Fe，Cu，Cd and Pb in the injection are below or near 1mg／l.The test of abnor-mal toxicity is negative. The quality of the injection meets the requirements of both the ChinesePharmacopoeia and the United States Pharmacopoeia. The chemical yield is（92±2）％while thetime of operation is＜3h.Key words ~(67)Ga citrate injection Butylacetate Solvent extraction