Abstract: The cross flow filtration of the three systems containing typical precipitates:crystalline (BaSO 4) ,non crystalline (Zr 3(PO 4) 4) and synthetic (simulated HLLW) is studied.The effects of the system,pore size,solid content,pressure difference and cross flow velocity on the filtration are investigated.The results of the experiments show there is a critical value of cross flow velocity and solid content.The values have an effect on the result of the filtration.The effect of pressure difference depends on the condensability of filter cake.The filtration property of simulated HLLW is similar to the system of Zr 3(PO 4) 4. The cross flow filtration of the simulated HLLW by ceramic micro porous pipe (0.2 μm pore size) is proved on long run test.The filtration velocity is kept at 150 L/(h·m 2). The solid content in the filtrate is less than 2 mg/L.