Abstract: In this experiment, the migration of ⁹⁰Sr in the weakly weathered granite was studied by using the penetration curve of ³H and ⁹⁰Sr with the method of dynamic column experiment. The migration parameters of ⁹⁰Sr in the weakly weathered granite were obtained. The flow rate was set at 1 mL/h during the test. With 10⁴ Bq ³H, the migration test has been carried out for 120 h. The peak activity concentration appeares at 8.0 hour, with the peak activity concentration of 213.4 kBq/L, and the penetration curve of ³H has no obvious tailing phenomenon. With 5×10⁴ Bq ⁹⁰Sr, the migration test has been carried out for 132 d. The peak activity concentration appeares on 27.4 day, with the peak activity concentration of 46.26 kBq/L, and the concentration of ⁹⁰Sr shows an obvious tailing phenomenon in the decreasing stage. By means of numerical simulation, the vertical dispersion of weakly weathered granite is 3.03 cm. By comparing the fitting results of ⁹⁰Sr in weakly weathered granite under the following four models: equilibrium model, two-site sorption model, dual-porosity model, and dual-porosity model with two-site sorption, it is found that the fitting results of the four models are quite different. Dual-porosity model with two-site sorption can better explain the non-equilibrium adsorption phenomenon during the migration of nuclides in the weakly weathered granite by introducing the water content in the non-moving region, the first-order rate coefficient of solute exchange and the first order rate coefficient of non-equilibrium adsorption. The results show that distribution coefficient of ⁹⁰Sr in weakly weathered granite is 1.23 mL/g, the first order rate coefficient of solute exchange is 0.227 /d, and the first order rate coefficient of non-equilibrium adsorption is 0.118 /d.