Current Researches and Progress on Preparation of ¹⁸F Labeled Positron Radiopharmacueticals

In the tumor receptor researches by positron emission tomography, fluorine ¹⁸F-labeled RGD peptides target α_vβ₃ integrin which is highly expressed in tumor angiogenesis and tumor endometrial cells, and thus can reveal tumor angiogenesis, proliferation and metastasis. The relative researches are recently highlighted and focused, meanwhile present the progress of ¹⁸F labeled small peptides. In this review, current researches and progress on the preparation of ¹⁸F labeled positron radiophamaceuticals will be introduced.