Advances in Determination Methods of <sup>241</sup>Am in Urine Samples

GAO Jia-min; WEN Fu-ping; LOU Hai-lin

doi:10.7538/hhx.2019.YX.2018067

Journal of Nuclear and Radiochemistry > 2020 > 42(1): 13-21. > DOI: 10.7538/hhx.2019.YX.2018067

GAO Jia-min, WEN Fu-ping, LOU Hai-lin. Advances in Determination Methods of ²⁴¹Am in Urine Samples[J]. Journal of Nuclear and Radiochemistry, 2020, 42(1): 13-21. DOI: 10.7538/hhx.2019.YX.2018067

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Advances in Determination Methods of ²⁴¹Am in Urine Samples

China Institute of Atomic Energy, P. O. Box 275(15), Beijing 102413, China

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Abstract

Abstract

²⁴¹Am is one of the most toxic transuranic nuclides due to its long half-life and α-particle emission, which needs to be surveilled in both internal individual exposure routine monitoring for workers and emergency rapid analysis. This paper aims to critically review some aspects of determination of ²⁴¹Am in the urine sample. A typical radiochemical analysis procedure consists of calcium phosphate or oxalate co-precipitation, extraction chromatography with DGA or TRU resin, source preparation by electrodeposition in ammonium sulfate or oxalate or micro co-precipitation with Nd/CeF₃. Newly progress in the measurement techniques of ²⁴¹Am in urine, especially the capabilities of various mass spectrometry including radioactivity measuring instruments like alpha spectrometry, liquid scintillation spectrometry and gamma spectrometry or non-radioactive measuring instruments like mass spectrometry(ICP-MS, AMS etc.) has also been mentioned in this review.
- urine sample,
- ²⁴¹Am,
- measurement,
- extraction chromatography,
- ion-exchange,
- alpha-spectrometry,
- liquid scintillation,
- mass spectrometry

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References (42)

References

[1]	舒尔茨.镅化学[M].唐任寰,高宏成,译.北京:原子能出版社,1981.
[2]	沙连茂.环境中的超铀元素及其放射化学分析的进展[J].辐射防护,1998(3):46-59.
[3]	Hou X, Roos P. Critical comparison of radiometric and mass spectrometric methods for the determination of radionuclides in environmental, biological and nuclear waste samples[J]. Anal Chim Acta, 2008, 608(2): 105-139.
[4]	周培德.我国核电发展中少数锕系核素积累量预测[J]. 核科学与工程,2000(1):11-17.
[5]	强亦忠,石玉成.环境中的超铀元素及其迁移[J].国外医学(放射医学分册),1985(1):7-11.
[6]	Xiao G, Saunders D, Jones R L, et al. Determination of Am-241 in urine using sector field inductively coupled plasma mass spectrometry(SF-ICP-MS)[J]. J Radioanal Nucl Chem, 2014, 301(1): 285-291.
[7]	Sadi B B, Li C, Masoud A, et al. An emergency urine bioassay method for Am-241 by extraction chromatography and liquid scintillation counting[J]. Radiat Prot Dosim, 2010, 141(2): 134-139.
[8]	Alvarez A, Navarro N. Method for actinides and Sr-90 determination in urine samples[J]. Appl Radiat Isotopes, 1996, 47(9-10): 869.
[9]	Maxwell S L. Rapid analysis of emergency urine and water samples[J]. J Radioanal Nucl Chem, 2008, 275(3): 497-502.
[10]	Dulanska S, Bilohuscin J, Remenec B, et al. Determination of Pu-239, Am-241 and Sr-90 in urine using pre-filter material and combined sorbents AnaLig (R) Pu-02, AnaLig (R) Sr-01, DGA (R) resin[J]. J Radioanal Nucl Chem, 2015, 304(1): 127-132.
[11]	Lovett M B, Boggis S J, Blowers P. The determination of alpha-emitting nuclides of plutonium, americium and curium in environmental materials, part 1: sea water[M]. UK: Ministry of Agriculture, Fisheries and Food, Lowestoft. Directorate of Fisheries Research, 1990.
[12]	Dacheux N, Aupiais J. Determination of low concentrations of americium and curium by photon/electron rejecting alpha liquid scintillation[J]. Anal Chim Acta, 1998, 363(2-3): 279-294.
[13]	赵敏,李云龙.尿中镅、锔的测定[J].辐射防护,1980(2):1-9.
[14]	Horwitz E P, Mcalister D R, Bond A H, et al. Novel extraction of chromatographic resins based on tetraalkyldiglycolamides: characterization and potential applications[J]. Solvent Extr Ion Exch, 2005, 23: 319-344.
[15]	Eichrom Technologies LLC. TRU resin[EB/OL]. USA: Eichrom Technologies, 2008[2018-04-28].
[16]	Eichrom Technologies LLC. ACTINIDE resin[EB/OL]. USA: Eichrom Technologies, 2008[2018-04-28].
[17]	Arginelli D, Battisti P, Giardina I. Extraction chromatography with DGA resin for the determination of americium and curium in biological samples by high resolution alpha spectrometry[J]. J Radioanal Nucl Chem, 2016, 309(1): 279-284.
[18]	Maxwell S L, Culligan B K. New column separation method for emergency urine samples[J]. J Radioanal Nucl Chem, 2009, 279: 105-111.
[19]	Maxwell S L, Jones V D. Rapid determination of actinides in urine by inductively coupled plasma mass spectrometry and alpha spectrometry: a hybrid approach[J]. Talanta, 2009, 80(1): 143-150.
[20]	Hou X, Olsson M, Togneri L, et al. Present status and perspective of radiochemical analysis of radionuclides in Nordic countries[J]. J Radioanal Nucl Chem, 2016, 309(3): 1283-1319.
[21]	邱咏梅,杨勇.α能谱法测量尿中的Am-241[J].中国核科技报告,2006(1):48-57.
[22]	Ballestra S, Fukai R. An improved radiochemical procedure for low-level measurements of americium in environmental matrices[J]. Talanta, 1983, 30(1): 45-48.
[23]	Hampson B L, Tennant D. Simultaneous determination of actinide nuclides in environmental materials by solvent extraction and alpha spectrometry[J]. Analyst, 1973, 98(173): 873-885.
[24]	Zagyvai M, Vajda N, Groska J, et al. Assay of actinides in human urine by rapid method[J]. J Radioanal Nucl Chem, 2017, 314(1): 49-58.
[25]	Kelly L R. Optimization of the microprecipitation procedure for nuclear forensics applications[D]. US, NV: University of Nevada Las Vegas, 2009.
[26]	Jung-Suk O, Phillip E W, Ian W C, et al. Evaluation of three electrodeposition procedures for uranium, plutonium and americium[J]. Appl Radiat Isotopes, 2014, 87: 233-237.
[27]	Knab D.少量环境样品中镅的测定[J].金秀华,译.国外医学(放射医学分册),1980(3):175-177.
[28]	赵清,徐春长,陈靖,等.镅的电沉积：电镀制源[J].中国计量,2008(8):62-63.
[29]	Talvitie N A. Electrodeposition of actinides for alpha spectrometric determination[J]. Anal Chem, 1972, 44(2): 280-283.
[30]	孟昭菊,党云博,涂兴明,等.镅、钚电沉积液的选择[C]∥第十三届全国核化学与放射化学学术研讨会论文摘要集.大理：中国核学会核化学与放射化学分会，2014:104.
[31]	喻正伟,叶宏生,林敏,等.电刷镀法制备大面积²⁴¹Am放射源[J].核化学与放射化学,2015,37(3):166-170.
[32]	ASTM International. ASTM C1163-14, standard practice for mounting actinides for alpha spectrometry using neodymium fluoride[S]. US: ASTM, 2014.
[33]	Vasile M, Jacobs K, Bruggeman M, et al. On the sequential separation and quantification of ²³⁷Np, ²⁴¹Am, thorium, plutonium, and uranium isotopes in environmental and urine samples[J]. Appl Radiat Isotopes, 2018, 134: 455-460.
[34]	Dai X, Christl M, Kramer- Tremblay S, et al. Determination of atto to femtogram levels of americium and curium isotopes in large-volume urine samples by compact accelerator mass spectrometry[J]. Anal Chem, 2016, 88(5): 2832-2837.
[35]	Holm E.α谱法测量锕系元素的评述[J].顾鼎祥，译.国外铀矿地质,1987(3):69-74.
[36]	McDowell W J, Case G N. Some applications of photon/electron-rejecting alpha liquid scintillation (PERALS) spectrometry to the assay of alpha emitters: TN 37831[R]. US: Technical Information Center, DOE, 1986.
[37]	Cadieux J R. Evaluation of a photoelectron-rejecting-alpha liquid-scintillation(PERALS) spectrometer for the measurement of alpha-emitting radionuclides (U)[J]. Nucl Instrum Meth Phys Res A, 1990, 299(1-3): 119-122.
[38]	Li C, Sadi B, Benkhedda K, et al. Method compare-son for Am-241 emergency urine bioassay[J]. Radiation Protection Dosimetry, 2010, 141(3): 228-232.
[39]	Christl M, Dai X, Lachner J, et al. Low energy AMS of americium and curium[J]. Nucl Instrum Methods Phys Res, Sect B, 2014, 331: 225-232.
[40]	Ketterer M E, Szechenyi S C. Determination of plutonium and other transuranic elements by inductively coupled plasma mass spectrometry: a historical perspective and new frontiers in the environmental sciences[J]. Spectrochim Acta, Part B, 2008, 63(7): 719-737.
[41]	Ridone S, Arginelli D, Berton G, et al. Radioanalytical determination of ^239+240Pu and ²⁴¹Am in bioassay samples by anion exchange and extraction chromatography: preliminary considerations about the two methods[J]. Czech J Phys, 2006, 56: D195-D201.
[42]	Hang W, Zhu L W, Zhong W W, et al. Separation of actinides at ultra-trace level from urine matrix using extraction chromatography-inductively coupled plasma mass spectrometry[J]. J Anal Atom Spectrom, 2004, 19(8): 966-972.