STUDY OF KINETICS IN LABELLING THE ADRENAL IMAGING AGENT NCL-6-I BY THE CROWN ETHER METHOD
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Graphical Abstract
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Abstract
Radioiodination of NCL-6-I is achieved by means of the crown ether method. Kinetics in the 18-C-6 crown ether medium is investigated. The results indicate that the isotopic exchange reaction between NCL-6-I and Na 125I is a second order reaction. The rate constant of reaction is determined by a straight line between -In (1-F) and t. Our results show that the crown ether labelling method is characterized by high yield, rapidity and conveniece.
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