PREPARATION OF ~(67)Ga-EDTMP AND ITS BIODISTRIBUTION IN RATS

Dependence of the labeling yield of 67 Ga EDTMP on concentration of EDTMP, reaction time, reaction temperature and pH is studied.In the case of optimum conditions,the labeling yield is more than 97 %.The stability of 67 Ga EDTMP at pH≈6 is examined. The biodistribution of 67 Ga EDTMP in rats is measured. The results show high skeletal uptake and T/NT value in 72 h.