STUDY OF LABELING ACETATE GLY-PHE WITH ~(18)F
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Graphical Abstract
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Abstract
Acetate GlyPhe (HGP) is indirectly labeled with 18F.The effcts of pH,reaction time,HGP concentration and the amount of catalyst HOBT on labeling yields are studied.The optimum conditions are∶pH=9.2,HGP concentration is 1 mg/mL, reaction time is 5 min at room temperature, under which the labeling yield is obtained to be 90%.
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