THE ROLE OF HYDROGEN ISOTOPE EFFECT IN CATALYTIC ADDITION REACTION——SYN-THESIS OF (4,5-~3H)-EXO-CIS-3,6-EPOXYHEXA-HYDROPHTHALIC ANHYDRIDE

Hydrogen isotope effect is found in the catalytic addition reaction-synthesis of (4.5-(?)H)-exp-cis-3,6-epoxyhexahydrophthalic anhydride and the isotope separation factor is related to the temperature by the equation lgαH-T = 0.04 ±138/T. Theoretical values of specific activities of the 3H-labelled compound calculated from the equation agree well with experimental values. The agreement proves that hydrogen isotope effect does exist on the palladium catalyst.